HER2 Knowledge Check+
Identification of HER2 IHC 0+ (with Faint/Incomplete Membrane Staining)
About This Initiative
This educational web-based resource is designed to support pathologists in accurately interpreting low levels of HER2 expression in metastatic breast cancer (mBC) cases using HER2 immunohistochemistry (IHC) staining, with a focus on identifying HER2 IHC 0+ (with faint/incomplete membrane staining).
How It Works
- Review HER2 IHC staining criteria reference
- Review and score 5 HER2 IHC staining cases (tap to magnify)
- Up to 2 attempts per case
- Digital Pathology Reviews
Medical Disclaimer
For U.S. health care professionals only. This educational resource is intended to support HER2 IHC evaluation and is not a substitute for independent professional judgment, applicable clinical guidelines, or institutional procedures. Final HER2 interpretation, classification, and reporting remain the responsibility of the reviewing pathologist.